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Archive for January 2012

eHealth: patients are changing, but not (yet) the Physicians

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Patients, be patient!, Mark Senak recommends.

” I can attach a cuff to my i-Pad which will then also take my blood pressure on my i-Pad and plot it out along with my weight in either chart or graph form by date and available for my physician. The problem is that my physician then hand enters the readings into my chart with a pen and paper. (…)

Patients are changing.  They are accessing medical information differently, they are storing it differently and they are consuming it more voraciously.  This access to medical information and tools means that many patients are more medically conversant and knowledgeable than the patient of just five years ago.  Medical literacy is likely on the rise.

It also changes the way physician and patient communicate.  Five years ago, I never would have considered the need for email between my physician and myself, thinking it impractical.  Today, I think a physician needs to have some portal of access for the exchange of data and information. (…)

The use of e-tools has become so ubiquitous, many physicians may not be aware the extent to which the patient experience is being changed.”

Senak, Mark. Patience Patients – Are e-Patients Waiting for e-Docs? Eye on FDA, 25th of January, 2012.
http://www.eyeonfda.com/eye_on_fda/2012/01/patience-patients-are-e-patients-waiting-for-e-docs.html

 

 

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Written by hbasset

January 27, 2012 at 5:45 pm

Posted in Uncategorized

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How many science journals?

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  • Estimation: <> 25-40,000 journals
  • 96% are published online
  • 8-10% are published under Open Access models
  • 20% of science articles are available free of charge
  • How many articles have been published ever (means since 1665)? est. 50 millions
  • Growth: 1.4 million of articles per year
  • There are 2,000 publishers but Top 3 (Elsevier, Springer, Wiley)  account for 42% of articles published
  • Elsevier itself publishes 250,000 articles a year in 2,000 journals
  • The biggest platform of ejournals, ScienceDirect, provides 240 million of downloads per year to 10 million of users
  • The cost of publishing a single online scientific journal article is estimated at $10,000
  • To purchase an article for an individual: $30-40
  • Average cost of a subscription for a library: $3,792 (average cost for a chemistry journal) up to $10,000
  • The most expensive: Biochimica & Biophysica Acta, $20,930 a year!

Sources:

– Article 50 million: an estimate of the number of scholarly articles in existence. Jinha, Arif E. Learned Publishing, Volume 23, Number 3, July 2010 , pp. 258-263
– Leggott, Mark. UPEI, Web of Science and Knowledge for all. Posted on: 14th of August 2010.
 – Björk B-C, Welling P, Laakso M, Majlender P, Hedlund T, et al. (2010) Open Access to the Scientific Journal Literature: Situation 2009. PLoS ONE 5(6): e11273. http://www.plosone.org/article/info:doi/10.1371/journal.pone.0011273
–  Fanelli D (2010) Do Pressures to Publish Increase Scientists’ Bias? An Empirical Support from US States Data. PLoS ONE 5(4): e10271. http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010271
– Ware, Mark and Mabe, Michael. The stm report : An overview of scientific and scholarly journals publishing. September 2009. Online: http://www.stm-assoc.org/news.php?id=255&PHPSESSID=3c5575d0663c0e04a4600d7f04afe91f

Written by hbasset

January 23, 2012 at 10:02 pm

Posted in Journals

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iPad: the pharma industry must gain a presence

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In the latest issue of Pharmaceutical Executive:

Pharma is not an industry known for launching headlong into new ideas and new ways of doing things—at least not without indulging in a considerable period of cautious study first. So its embrace of the iPad—both as a new sales tool and as a new way to communicate with and educate patients—stands out as somewhat anomalous. Granted, the sheer economic and cultural impact of the device, which was first released in April 2010, has been hard for any technologically focused industry to ignore: Apple sold 15 million iPads in the first nine months of launch. And its uptake among the medical profession has been particularly staggering. In May 2011, Manhattan Research reported that 30 percent of physicians in the U.S. already own an iPad, and this proportion will have already risen considerably, given that another 28 percent revealed they were planning to purchase one “in the next six months. (…)

But recognizing the iPad as a phenomenon and making a quick decision to embrace the hardware is just the beginning. The iPad revolution brings with it a new challenge, that of effective content creation… (…)

There are companies that appear to be getting it right, however. Johnson & Johnson’s psoriasis app for dermatologists and patients, which allows a quick and simple evaluation of the severity of their condition, has been averaging almost 60 downloads a day for well over a year. The reason for its success, explains Hunt, is that it is “pick-up-and-play, and immediately rewarding.”

On the sales/CRM side, Abbott‘s pilot app, developed by Oi, was successful because it was a “real closed loop solution,” says Ashley. In creating it, the agency went out with the sales reps to ascertain the various needs of the different clients: “It was a case of understanding that it wasn’t a matter of delivering a PowerPoint solution. The rep wants something that supports his conversation. (…)

Far from being a device to replace the sales rep, which has been one of the more hysterical reactions to the iPad, it serves to augment the relationship between reps and physicians. And the rep is more efficient in the relationship

Read further at:

Upton, Julian. iPad Apps: are you content with your content? Pharmaceutical Executive, January 2012. Online:
http://www.pharmexec.com/pharmexec/article/articleDetail.jsp?id=755081&pageID=1&sk=&date=

 

 

 

Written by hbasset

January 23, 2012 at 8:42 pm

Posted in Pharmaceutical Industry

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SharePoint for Life Sciences Companies: the ShareFest 2012 programme

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The ShareFest Conference, sponsored by NextDocs, will happen in April 2012, in Philadelphia.

Programme was realeased. It includes conferences around:

– Clinical data at Astra-Zeneca

– DMS at Liquent

– GXP quality system at IDT biologika

– Electronic submission with LORENZ

– Regulatory compliance at Roche

– Clinical trials documentation at Sanofi

– and many others

http://sharefestconference.com/all-sessions

 

Written by hbasset

January 23, 2012 at 8:15 pm

Posted in Pharmaceutical Industry

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Physicians do not like Patient Opinion Leaders (POL)

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After KOL, a new concept is growing… the idea that some pro-patients can influence enough all the other consumers, Elys Roberts explains in the latest Pharmaceutical Executive.

the healthcare ecosystem is now comprised of multiple stakeholders with a far more complex decision-making dynamic than existed just a few years ago. In addition, patients are not a single homogenous unit. Some may have little or no impact on treatment decisions or healthcare choices while others may take an active individual role. But the ones that we find really interesting are those taking on almost an ‘activist’ role, impacting not only their own healthcare, but potentially many, many others as well. We call this last group the “pro-patient.”

This is the pro-active patient. They are not just personally empowered and assertive, but broadcast their experiences, opinions, and objectives and therefore have a far wider sphere of influence. (…)

If you search them out, you will find this vocal minority active in online forums. They have become the de facto Patient Opinion Leaders (POL)—and just as every pharma company has a KOL strategy, they now need a POL strategy too. (…)

These people have always existed. What is different now is that Web 2.0 gives them a much broader audience. In the past their sphere of influence was limited to family and friends, but now their audience can be measured in thousands or millions. (…)

We saw some examples of the negative passion of pro-patient activity, railing against the consequences of side effects of medication, for example, but most of the pro-patients we spoke to had good intentions and saw themselves as providing a valuable service. (…)

This kind of pro-patient broadcasting clearly has the power to influence the physician/patient dynamic on a wide scale. Interestingly, when we asked physicians about this phenomenon, responses varied by country (more positive in the UK, less positive in Italy for instance), but overall physician reaction could be characterized as cautious at best. (…)

So perhaps surprisingly, even if a patient’s source of information is good, or may have been from a pro-patient who broadcasted with the best intentions to help educate, this can still be viewed less-than-positively by physicians.

(…)

Roberts, Elys and Sarah Phillipps. The emergence of the Pro-Patient. Pharmaceutical Executive, January 2012, pp.48-49
http://www.pharmexec.com/pharmexec/article/articleDetail.jsp?id=755084&sk=&date=&%0A%09%09%09&pageID=2

Written by hbasset

January 21, 2012 at 4:41 pm

Posted in Pharmaceutical Industry

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Open science: change is coming…

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In a very optimistic article, the New York Times reports some great milestones. Initiatives to make the scientific and medical research process more collaborative are gaining traction, as advocates of “open science” are launching open-access publications and social networking websites for researchers.

Some extracts:

advocates for “open science” say science can accomplish much more, much faster, in an environment of friction-free collaboration over the Internet. And despite a host of obstacles, including the skepticism of many established scientists, their ideas are gaining traction”

Some good stories are:

  • Public Library of Science (PLoS)
  •  ResearchGate — where scientists can answer one another’s questions, share papers and find collaborators — is rapidly gaining popularity. Its membership has mushroomed to more than 1.3 million. The Web site is a sort of mash-up of Facebook, Twitter and LinkedIn, with profile pages, comments, groups, job listings, and “like” and “follow” buttons. Only scientists are invited to pose and answer questions.Scientists populate their ResearchGate profiles with their real names, professional details and publications — data that the site uses to suggest connections with other members. Users can create public or private discussion groups, and share papers and lecture materials. ResearchGate is also developing a “reputation score” to reward members for online contributions. ResearchGate offers a simple yet effective end run around restrictive journal access with its “self-archiving repository.” Since most journals allow scientists to link to their submitted papers on their own Web sites, Dr. Madisch encourages his users to do so on their ResearchGate profiles. In addition to housing 350,000 papers (and counting), the platform provides a way to search 40 million abstracts and papers from other science databases. In 2011, ResearchGate reports, 1,620,849 connections were made, 12,342 questions answered and 842,179 publications shared
  •  ScienceOnline conference will have its sixth edition this year
Anyway, these advocates agreed that scientists have been “very inhibited and slow to adopt a lot of online tools.”
Hanging the status quo — opening data, papers, research ideas and partial solutions to anyone and everyone — is still far more idea than reality. Especially because Publishers have to defend their traditionnal business model: “They have shareholders, (…)They have to move the ship slowly.”
“Will the model of science magazines be the same 10 years from now? I highly doubt it,  I believe in evolution“, a publisher says.
Dr. Madisch, of ResearchGate, acknowledged that he might never reach many of the established scientists for whom social networking can seem like a foreign language or a waste of time. But wait, he said, until younger scientists weaned on social media and open-source collaboration start running their own labs.
We’re just at the beginning. The change is coming.”
Lin, Thomas. Cracking Open the Scientific Process. The New York Times, Posted on 17th of January 2012.

http://www.nytimes.com/2012/01/17/science/open-science-challenges-journal-tradition-with-web-collaboration.html?pagewanted=1&_r=1

Written by hbasset

January 17, 2012 at 8:53 pm

Are publishers the enemies of science?

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A provocative but interesting manifesto in The Guardian:

Publishers’ “rhetoric has traditionally been of partnering with scientists, but the truth is that for some time now scientific publishers have been anti-science and anti-publication. The Research Works Act, introduced in the US Congress on 16 December, amounts to a declaration of war by the publishers. (…)

All of this is great for the progress of science, which has always been based on the free flow of ideas, the sharing of data, and standing on the shoulders of giants 

But what’s good for science isn’t necessarily good for science publishers, whose interests have drifted far out of alignment with ours. Under the old model, publishers become the owners of the papers they publish, holding the copyright and selling copies around the world – a useful service in pre-internet days. But now that it’s a trivial undertaking to make a paper globally available, there is no reason why scientists need yield copyright to publishers. (…)

Open-access publishers such as the Public Library of Science are able to make a modest profit on a publication fee of $1,350 (£880). But traditional publishers have become used to making much more than this, and so resist the inevitable conversion to open access.

t’s hardly surprising that publishers would fight dirty to hang on to a business model where scientists do research that is largely publicly funded, and write manuscripts and prepare figures at no cost to the journal; other scientists perform peer-review for free; and other scientists handle the editorial tasks for free or for token stipends. The result of all this free and far-below-minimum-wage professional work is journal articles in which the publisher, which has done almost nothing, owns the copyright and is able to sell copies back to libraries at monopolistic costs, and to individuals at $30 or more per view.

What is surprising is how complicit scientists are in perpetuating this feudal system (…)

The bottom line for scientists is that many publishers have now made themselves our enemies instead of the allies they once were. Elsevier’s business does not make money by publishing our work, but by doing the exact opposite: restricting access to it. We must not be complicit in their newest attempt to cripple the progress of science”.

Dr Mike Taylor. Academic publishers have become the enemies of science. The Guardian, Online, the 16th of January 2012.
http://www.guardian.co.uk/science/2012/jan/16/academic-publishers-enemies-science

Written by hbasset

January 16, 2012 at 8:56 pm